Combination of multiple computational methods revealing specific sub-sectional recognition and hydrogen-bond dependent transportation of CKII peptide fragment in O-GlcNAc transferase

O-linked β-N-acetyl-D-glucosamine (O-GlcNAc) transferase (OGT) is an essential enzyme in many cellular physiological catalytic reactions that regulates protein O-GlcNAcylation. Aberrant O-GlcNAcylation is related to insulin resistance, diabetic complications, cancer and neurodegenerative diseases. U...

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Detalles Bibliográficos
Autores principales: Zhang, Xiao, Zhang, Zhiyang, Guo, Jia, Ma, Jing, Xie, Songqiang, Zhao, Yuan, Wang, Chaojie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8085782/
https://www.ncbi.nlm.nih.gov/pubmed/33995901
http://dx.doi.org/10.1016/j.csbj.2021.04.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8085782/
https://www.ncbi.nlm.nih.gov/pubmed/33995901
http://dx.doi.org/10.1016/j.csbj.2021.04.009

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