Computational study on the allosteric mechanism of Leishmania major IF4E-1 by 4E-interacting protein-1: Unravelling the determinants of m(7)GTP cap recognition

During their life cycle, Leishmania parasites display a fine-tuned regulation of the mRNA translation through the differential expression of isoforms of eukaryotic translation initiation factor 4E (LeishIF4Es). The interaction between allosteric modulators such as 4E-interacting proteins (4E-IPs) an...

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Detalles Bibliográficos
Autores principales: Hernández-Alvarez, Lilian, Oliveira Jr, Antonio B, Hernández-González, Jorge Enrique, Chahine, Jorge, Pascutti, Pedro Geraldo, de Araujo, Alexandre Suman, de Souza, Fátima Pereira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8085901/
https://www.ncbi.nlm.nih.gov/pubmed/33995900
http://dx.doi.org/10.1016/j.csbj.2021.03.036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8085901/
https://www.ncbi.nlm.nih.gov/pubmed/33995900
http://dx.doi.org/10.1016/j.csbj.2021.03.036

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