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Cytolytic activity score as a biomarker for antitumor immunity and clinical outcome in patients with gastric cancer

BACKGROUND: A simple measure of immune cytolytic activity (CYT) base on mRNA expression levels of two genes, GZMA and PRF1, was recently reported. Here, we aimed to evaluate the CYT score's potential as a measure of antitumor immunity and predictor of clinical outcome in gastric cancer (GC) pat...

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Detalles Bibliográficos
Autores principales: Hu, Qingjiang, Nonaka, Kentaro, Wakiyama, Hiroaki, Miyashita, Yu, Fujimoto, Yoshiaki, Jogo, Tomoko, Hokonohara, Kentaro, Nakanishi, Ryota, Hisamatsu, Yuichi, Ando, Koji, Kimura, Yasue, Masuda, Takaaki, Oki, Eiji, Mimori, Koshi, Oda, Yoshinao, Mori, Masaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8085935/
https://www.ncbi.nlm.nih.gov/pubmed/33769705
http://dx.doi.org/10.1002/cam4.3828