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Prospective experimental treatment of colorectal cancer patients based on organoid drug responses

BACKGROUND: Organoid technology has recently emerged as a powerful tool to assess drug sensitivity of individual patient tumors in vitro. Organoids may therefore represent a new avenue for precision medicine, as this circumvents many of the complexities associated with DNA- or transcriptional-profil...

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Detalles Bibliográficos
Autores principales: Ooft, S.N., Weeber, F., Schipper, L., Dijkstra, K.K., McLean, C.M., Kaing, S., van de Haar, J., Prevoo, W., van Werkhoven, E., Snaebjornsson, P., Hoes, L.R., Chalabi, M., van der Velden, D., van Leerdam, M., Boot, H., Grootscholten, C., Huitema, A.D.R., Bloemendal, H.J., Cuppen, E., Voest, E.E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086019/
https://www.ncbi.nlm.nih.gov/pubmed/33887686
http://dx.doi.org/10.1016/j.esmoop.2021.100103