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Galactosaminogalactan activates the inflammasome to provide host protection

Inflammasomes are important sentinels of innate immune defense activated in response to diverse stimuli, including pathogen-associated molecular patterns (PAMPs)(1). Activation of the inflammasome provides host defense against aspergillosis(2,3), a major health concern for immunocompromised patients...

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Detalles Bibliográficos
Autores principales: Briard, Benoit, Fontaine, Thierry, Samir, Parimal, Place, David E., Muszkieta, Laetitia, Malireddi, R.K. Subbarao, Karki, Rajendra, Christgen, Shelbi, Bomme, Perrine, Vogel, Peter, Beau, Rémi, Mellado, Emilia, Ibrahim-Granet, Oumaima, Henrissat, Bernard, Kalathur, Ravi C, Robinson, Cam, Latgé, Jean-Paul, Kanneganti, Thirumala-Devi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086055/
https://www.ncbi.nlm.nih.gov/pubmed/33268895
http://dx.doi.org/10.1038/s41586-020-2996-z