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Crosstalk between microRNA expression and DNA methylation drives the hormone-dependent phenotype of breast cancer

BACKGROUND: Abnormal DNA methylation is observed as an early event in breast carcinogenesis. However, how such alterations arise is still poorly understood. microRNAs (miRNAs) regulate gene expression at the post-transcriptional level and play key roles in various biological processes. Here, we inte...

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Detalles Bibliográficos
Autores principales: Aure, Miriam Ragle, Fleischer, Thomas, Bjørklund, Sunniva, Ankill, Jørgen, Castro-Mondragon, Jaime A., Børresen-Dale, Anne-Lise, Tost, Jörg, Sahlberg, Kristine K., Mathelier, Anthony, Tekpli, Xavier, Kristensen, Vessela N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086068/
https://www.ncbi.nlm.nih.gov/pubmed/33926515
http://dx.doi.org/10.1186/s13073-021-00880-4