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Crosstalk between microRNA expression and DNA methylation drives the hormone-dependent phenotype of breast cancer
BACKGROUND: Abnormal DNA methylation is observed as an early event in breast carcinogenesis. However, how such alterations arise is still poorly understood. microRNAs (miRNAs) regulate gene expression at the post-transcriptional level and play key roles in various biological processes. Here, we inte...
Autores principales: | Aure, Miriam Ragle, Fleischer, Thomas, Bjørklund, Sunniva, Ankill, Jørgen, Castro-Mondragon, Jaime A., Børresen-Dale, Anne-Lise, Tost, Jörg, Sahlberg, Kristine K., Mathelier, Anthony, Tekpli, Xavier, Kristensen, Vessela N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086068/ https://www.ncbi.nlm.nih.gov/pubmed/33926515 http://dx.doi.org/10.1186/s13073-021-00880-4 |
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