Cargando…
Ablation of interleukin-19 improves motor function in a mouse model of amyotrophic lateral sclerosis
Neuroinflammation by activated microglia and astrocytes plays a critical role in progression of amyotrophic lateral sclerosis (ALS). Interleukin-19 (IL-19) is a negative-feedback regulator that limits pro-inflammatory responses of microglia in an autocrine and paracrine manner, but it remains unclea...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086093/ https://www.ncbi.nlm.nih.gov/pubmed/33931083 http://dx.doi.org/10.1186/s13041-021-00785-8 |