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Ablation of interleukin-19 improves motor function in a mouse model of amyotrophic lateral sclerosis

Neuroinflammation by activated microglia and astrocytes plays a critical role in progression of amyotrophic lateral sclerosis (ALS). Interleukin-19 (IL-19) is a negative-feedback regulator that limits pro-inflammatory responses of microglia in an autocrine and paracrine manner, but it remains unclea...

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Detalles Bibliográficos
Autores principales:	Komiya, Hiroyasu, Takeuchi, Hideyuki, Ogawa, Yuki, Suzuki, Kosuke, Ogasawara, Akihiro, Takahashi, Keita, Azuma, Yasu-Taka, Doi, Hiroshi, Tanaka, Fumiaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086093/ https://www.ncbi.nlm.nih.gov/pubmed/33931083 http://dx.doi.org/10.1186/s13041-021-00785-8

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