Dichloroacetate and PX-478 exhibit strong synergistic effects in a various number of cancer cell lines

BACKGROUND: One key approach for anticancer therapy is drug combination. Drug combinations can help reduce doses and thereby decrease side effects. Furthermore, the likelihood of drug resistance is reduced. Distinct alterations in tumor metabolism have been described in past decades, but metabolism...

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Detalles Bibliográficos
Autores principales: Parczyk, Jonas, Ruhnau, Jérôme, Pelz, Carsten, Schilling, Max, Wu, Hao, Piaskowski, Nicole Nadine, Eickholt, Britta, Kühn, Hartmut, Danker, Kerstin, Klein, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086110/
https://www.ncbi.nlm.nih.gov/pubmed/33931028
http://dx.doi.org/10.1186/s12885-021-08186-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086110/
https://www.ncbi.nlm.nih.gov/pubmed/33931028
http://dx.doi.org/10.1186/s12885-021-08186-9

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