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Dichloroacetate and PX-478 exhibit strong synergistic effects in a various number of cancer cell lines
BACKGROUND: One key approach for anticancer therapy is drug combination. Drug combinations can help reduce doses and thereby decrease side effects. Furthermore, the likelihood of drug resistance is reduced. Distinct alterations in tumor metabolism have been described in past decades, but metabolism...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086110/ https://www.ncbi.nlm.nih.gov/pubmed/33931028 http://dx.doi.org/10.1186/s12885-021-08186-9 |