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Overexpression of hepatic serum amyloid A1 in mice increases IL-17-producing innate immune cells and decreases bone density
Serum amyloid A (SAA) is an acute-phase protein produced primarily in the liver that plays a key role in both the initiation and maintenance of inflammation. Rapidly secreted SAA induces neutrophilia at inflammatory sites, initiating inflammation and inducing the secretion of various cytokines, incl...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086136/ https://www.ncbi.nlm.nih.gov/pubmed/33781747 http://dx.doi.org/10.1016/j.jbc.2021.100595 |