Downregulation of PDGFRß Signaling Overcomes Crizotinib Resistance in a TYRO3 and ALK Mutated Neuroendocrine-Like Tumor

Patient-derived xenografts provide significant advantages over long-term passage cell lines when investigating efficacy of treatments for solid tumors. Our laboratory encountered a high-grade, metastatic, neuroendocrine-like tumor from a pediatric patient that presented with a unique genetic profile...

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Detalles Bibliográficos
Autores principales: Quinn, Colin H., Beierle, Andee M., Williams, Adele P., Marayati, Raoud, Bownes, Laura V., Markert, Hooper R., Aye, Jamie M., Stewart, Jerry E., Mroczek-Musulman, Elizabeth, Crossman, David K., Yoon, Karina J., Beierle, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086143/
https://www.ncbi.nlm.nih.gov/pubmed/33887553
http://dx.doi.org/10.1016/j.tranon.2021.101099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086143/
https://www.ncbi.nlm.nih.gov/pubmed/33887553
http://dx.doi.org/10.1016/j.tranon.2021.101099

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