A novel peptide antagonist of the human growth hormone receptor

Excess circulating human growth hormone (hGH) in vivo is linked to metabolic and growth disorders such as cancer, diabetes, and acromegaly. Consequently, there is considerable interest in developing antagonists of hGH action. Here, we present the design, synthesis, and characterization of a 16-resid...

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Detalles Bibliográficos
Autores principales: Basu, Reetobrata, Nahar, Khairun, Kulkarni, Prateek, Kerekes, Olivia, Sattler, Maya, Hall, Zachary, Neggers, Sebastian, Holub, Justin M., Kopchick, John J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086144/
https://www.ncbi.nlm.nih.gov/pubmed/33774052
http://dx.doi.org/10.1016/j.jbc.2021.100588

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086144/
https://www.ncbi.nlm.nih.gov/pubmed/33774052
http://dx.doi.org/10.1016/j.jbc.2021.100588

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