Cargando…

Activation of Notch3 in osteoblasts/osteocytes causes compartment-specific changes in bone remodeling

Notch receptors maintain skeletal homeostasis. NOTCH1 and 2 have been studied for their effects on bone remodeling. Although NOTCH3 plays a significant role in vascular physiology, knowledge about its function in other cellular environments, including bone, is limited. The present study was conducte...

Descripción completa

Detalles Bibliográficos
Autores principales: Canalis, Ernesto, Zanotti, Stefano, Schilling, Lauren, Eller, Tabitha, Yu, Jungeun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086145/
https://www.ncbi.nlm.nih.gov/pubmed/33774049
http://dx.doi.org/10.1016/j.jbc.2021.100583