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Conformational flexibility and structural variability of SARS-CoV2 S protein

Spike (S) glycoprotein of SARS-CoV2 exists chiefly in two conformations, open and closed. Most previous structural studies on S protein have been conducted at pH 8.0, but knowledge of the conformational propensities under both physiological and endosomal pH conditions is important to inform vaccine...

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Detalles Bibliográficos
Autores principales: Pramanick, Ishika, Sengupta, Nayanika, Mishra, Suman, Pandey, Suman, Girish, Nidhi, Das, Alakta, Dutta, Somnath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086150/
https://www.ncbi.nlm.nih.gov/pubmed/33932324
http://dx.doi.org/10.1016/j.str.2021.04.006