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Age of ovarian cancer diagnosis among BRIP1, RAD51C, and RAD51D mutation carriers identified through multi-gene panel testing

BACKGROUND: Professional society guidelines recommend risk-reducing salpingo-oophorectomy (RRSO) for women with pathogenic variants (PVs) in ovarian cancer-risk genes. Personalization of that intervention is based on gene-specific phenotypes; however, the age of ovarian cancer diagnosis in women wit...

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Detalles Bibliográficos
Autores principales: Cummings, Shelly, Roman, Susana San, Saam, Jennifer, Bernhisel, Ryan, Brown, Krystal, Lancaster, Johnathan M., Usha, Lydia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086272/
https://www.ncbi.nlm.nih.gov/pubmed/33926482
http://dx.doi.org/10.1186/s13048-021-00809-w