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Age of ovarian cancer diagnosis among BRIP1, RAD51C, and RAD51D mutation carriers identified through multi-gene panel testing
BACKGROUND: Professional society guidelines recommend risk-reducing salpingo-oophorectomy (RRSO) for women with pathogenic variants (PVs) in ovarian cancer-risk genes. Personalization of that intervention is based on gene-specific phenotypes; however, the age of ovarian cancer diagnosis in women wit...
Autores principales: | Cummings, Shelly, Roman, Susana San, Saam, Jennifer, Bernhisel, Ryan, Brown, Krystal, Lancaster, Johnathan M., Usha, Lydia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086272/ https://www.ncbi.nlm.nih.gov/pubmed/33926482 http://dx.doi.org/10.1186/s13048-021-00809-w |
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