HRP2 and HRP3 cross-reactivity and implications for HRP2-based RDT use in regions with Plasmodium falciparum hrp2 gene deletions

BACKGROUND: The Plasmodium falciparum antigen histidine rich protein 2 (HRP2) is a preferred target for malaria rapid diagnostic tests (RDTs) because of its abundant production by the parasite and thermal stability. As a result, a majority of RDTs procured globally target this antigen. However, prev...

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Detalles Bibliográficos
Autores principales: Kong, Amy, Wilson, Scott A., Ah, Yong, Nace, Douglas, Rogier, Eric, Aidoo, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086288/
https://www.ncbi.nlm.nih.gov/pubmed/33926477
http://dx.doi.org/10.1186/s12936-021-03739-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086288/
https://www.ncbi.nlm.nih.gov/pubmed/33926477
http://dx.doi.org/10.1186/s12936-021-03739-6

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