Inhibition of RNA-binding protein HuR reduces glomerulosclerosis in experimental nephritis

Recent identification of an RNA-binding protein (HuR) that regulates mRNA turnover and translation of numerous transcripts via binding to an ARE in their 3′-UTR involved in inflammation and is abnormally elevated in varied kidney diseases offers a novel target for the treatment of renal inflammation...

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Detalles Bibliográficos
Autores principales: Liu, Simeng, Huang, Zhimin, Tang, Anna, Wu, Xiaoqing, Aube, Jeffrey, Xu, Liang, Xing, Changying, Huang, Yufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086301/
https://www.ncbi.nlm.nih.gov/pubmed/32478392
http://dx.doi.org/10.1042/CS20200193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086301/
https://www.ncbi.nlm.nih.gov/pubmed/32478392
http://dx.doi.org/10.1042/CS20200193

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