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Knockdown of MCM8 inhibits development and progression of bladder cancer in vitro and in vivo

BACKGROUND: Bladder cancer is a frequently diagnosed urinary system tumor, whose mortality remains rising. Minichromosome maintenance eight homologous recombination repair factor (MCM8), a newly discovered MCM family member, has been shown to be required for DNA replication. Unfortunately, little is...

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Detalles Bibliográficos
Autores principales: Zhu, Wei, Gao, Fei, Zhou, Hongyi, Jin, Ke, Shao, Jianfeng, Xu, Zhuoqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086360/
https://www.ncbi.nlm.nih.gov/pubmed/33931059
http://dx.doi.org/10.1186/s12935-021-01948-2