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The safety and tolerability of alkaloids from Alstonia scholaris leaves in healthy Chinese volunteers: a single-centre, randomized, double-blind, placebo-controlled phase I clinical trial

CONTEXT: Capsule of alkaloids from the leaf of Alstonia scholaris (L.) R.Br. (Apocynaceae) (CALAS) is a new investigational botanical drug (No. 2011L01436) for bronchitis, post-infectious cough and asthma. OBJECTIVE: To observe the clinical safety and tolerability of CALAS. MATERIALS AND METHODS: Su...

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Detalles Bibliográficos
Autores principales: Gou, Zhong-Ping, Zhao, Yun-Li, Zou, Lin-Ling, Wang, Ying, Shu, Shi-Qing, Zhu, Xiao-Hong, Zheng, Li, Shen, Qi, Luo, Zhu, Miao, Jia, Wang, Yong-Sheng, Luo, Xiao-Dong, Feng, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086589/
https://www.ncbi.nlm.nih.gov/pubmed/33899689
http://dx.doi.org/10.1080/13880209.2021.1893349