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The safety and tolerability of alkaloids from Alstonia scholaris leaves in healthy Chinese volunteers: a single-centre, randomized, double-blind, placebo-controlled phase I clinical trial
CONTEXT: Capsule of alkaloids from the leaf of Alstonia scholaris (L.) R.Br. (Apocynaceae) (CALAS) is a new investigational botanical drug (No. 2011L01436) for bronchitis, post-infectious cough and asthma. OBJECTIVE: To observe the clinical safety and tolerability of CALAS. MATERIALS AND METHODS: Su...
Autores principales: | Gou, Zhong-Ping, Zhao, Yun-Li, Zou, Lin-Ling, Wang, Ying, Shu, Shi-Qing, Zhu, Xiao-Hong, Zheng, Li, Shen, Qi, Luo, Zhu, Miao, Jia, Wang, Yong-Sheng, Luo, Xiao-Dong, Feng, Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086589/ https://www.ncbi.nlm.nih.gov/pubmed/33899689 http://dx.doi.org/10.1080/13880209.2021.1893349 |
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