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The PTP1B mutant PTP1B∆2–4 is a positive regulator of the JAK/STAT signalling pathway in Hodgkin lymphoma

The neoplastic Hodgkin/Reed-Sternberg (HRS) cells of classical Hodgkin lymphoma (cHL) depend on chronic activation of the Janus kinase (JAK)/signal transducer and activator of transcription (STAT) signalling pathways to maintain survival and proliferation. Accumulating reports highlight the importan...

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Detalles Bibliográficos
Autores principales: Zahn, Malena, Kaluszniak, Bianca, Möller, Peter, Marienfeld, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086765/
https://www.ncbi.nlm.nih.gov/pubmed/33382412
http://dx.doi.org/10.1093/carcin/bgaa144