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Transcriptome-wide investigation of stop codon readthrough in Saccharomyces cerevisiae

Translation of mRNA into a polypeptide is terminated when the release factor eRF1 recognizes a UAA, UAG, or UGA stop codon in the ribosomal A site and stimulates nascent peptide release. However, stop codon readthrough can occur when a near-cognate tRNA outcompetes eRF1 in decoding the stop codon, r...

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Detalles Bibliográficos
Autores principales: Mangkalaphiban, Kotchaphorn, He, Feng, Ganesan, Robin, Wu, Chan, Baker, Richard, Jacobson, Allan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087045/
https://www.ncbi.nlm.nih.gov/pubmed/33878104
http://dx.doi.org/10.1371/journal.pgen.1009538