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Human parvovirus B19 interacts with globoside under acidic conditions as an essential step in endocytic trafficking

The glycosphingolipid (GSL) globoside (Gb4) is essential for parvovirus B19 (B19V) infection. Historically considered the cellular receptor of B19V, the role of Gb4 and its interaction with B19V are controversial. In this study, we applied artificial viral particles, genetically modified cells, and...

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Detalles Bibliográficos
Autores principales: Bieri, Jan, Leisi, Remo, Bircher, Cornelia, Ros, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087101/
https://www.ncbi.nlm.nih.gov/pubmed/33878123
http://dx.doi.org/10.1371/journal.ppat.1009434