Novel fluorescent-based reporter cell line engineered for monitoring homologous recombination events

Homologous recombination (HR) faithfully restores DNA double-strand breaks. Defects in this HR repair pathway are associated with cancer predisposition. In genetic engineering, HR has been used extensively to study gene function and it represents an ideal method of gene therapy for single gene disor...

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Detalles Bibliográficos
Autores principales: Bernardi, Alejandra, Gobelli, Dino, Serna, Julia, Nawrocka, Paulina, March-Rosselló, Gabriel, Orduña, Antonio, Kozlowski, Piotr, Simarro, María, de la Fuente, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087102/
https://www.ncbi.nlm.nih.gov/pubmed/33930025
http://dx.doi.org/10.1371/journal.pone.0237413

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087102/
https://www.ncbi.nlm.nih.gov/pubmed/33930025
http://dx.doi.org/10.1371/journal.pone.0237413

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