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Novel fluorescent-based reporter cell line engineered for monitoring homologous recombination events
Homologous recombination (HR) faithfully restores DNA double-strand breaks. Defects in this HR repair pathway are associated with cancer predisposition. In genetic engineering, HR has been used extensively to study gene function and it represents an ideal method of gene therapy for single gene disor...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087102/ https://www.ncbi.nlm.nih.gov/pubmed/33930025 http://dx.doi.org/10.1371/journal.pone.0237413 |