Leonurine-Repressed miR-18a-5p/SOCS5/JAK2/STAT3 Axis Activity Disrupts CML malignancy

Leonurine, an active natural alkaloid compound isolated from Herba leonuri, has been reported to exhibit promising anticancer activity in solid tumors. The aim of this study was to explore whether leonurine is able to inhibit chronic myeloid leukemia (CML) malignancy. Here, we found that leonurine d...

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Detalles Bibliográficos
Autores principales: Liu, Hui-Min, Guo, Chun-Ling, Zhang, Yao-Fang, Chen, Jian-Fang, Liang, Zhi-Peng, Yang, Lin-Hua, Ma, Yan-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087248/
https://www.ncbi.nlm.nih.gov/pubmed/33935775
http://dx.doi.org/10.3389/fphar.2021.657724

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087248/
https://www.ncbi.nlm.nih.gov/pubmed/33935775
http://dx.doi.org/10.3389/fphar.2021.657724

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