Transcriptome prediction performance across machine learning models and diverse ancestries

Transcriptome prediction methods such as PrediXcan and FUSION have become popular in complex trait mapping. Most transcriptome prediction models have been trained in European populations using methods that make parametric linear assumptions like the elastic net (EN). To potentially further optimize...

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Detalles Bibliográficos
Autores principales: Okoro, Paul C., Schubert, Ryan, Guo, Xiuqing, Johnson, W. Craig, Rotter, Jerome I., Hoeschele, Ina, Liu, Yongmei, Im, Hae Kyung, Luke, Amy, Dugas, Lara R., Wheeler, Heather E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087249/
https://www.ncbi.nlm.nih.gov/pubmed/33937878
http://dx.doi.org/10.1016/j.xhgg.2020.100019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087249/
https://www.ncbi.nlm.nih.gov/pubmed/33937878
http://dx.doi.org/10.1016/j.xhgg.2020.100019

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