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Transcriptome prediction performance across machine learning models and diverse ancestries
Transcriptome prediction methods such as PrediXcan and FUSION have become popular in complex trait mapping. Most transcriptome prediction models have been trained in European populations using methods that make parametric linear assumptions like the elastic net (EN). To potentially further optimize...
Autores principales: | Okoro, Paul C., Schubert, Ryan, Guo, Xiuqing, Johnson, W. Craig, Rotter, Jerome I., Hoeschele, Ina, Liu, Yongmei, Im, Hae Kyung, Luke, Amy, Dugas, Lara R., Wheeler, Heather E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087249/ https://www.ncbi.nlm.nih.gov/pubmed/33937878 http://dx.doi.org/10.1016/j.xhgg.2020.100019 |
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