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Quantifying noxious-evoked baseline sensitivity in neonates to optimise analgesic trials

Despite the high burden of pain experienced by hospitalised neonates, there are few analgesics with proven efficacy. Testing analgesics in neonates is experimentally and ethically challenging and minimising the number of neonates required to demonstrate efficacy is essential. EEG (electroencephalogr...

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Detalles Bibliográficos
Autores principales: Cobo, Maria M, Hartley, Caroline, Gursul, Deniz, Andritsou, Foteini, van der Vaart, Marianne, Schmidt Mellado, Gabriela, Baxter, Luke, Duff, Eugene P, Buckle, Miranda, Evans Fry, Ria, Green, Gabrielle, Hoskin, Amy, Rogers, Richard, Adams, Eleri, Moultrie, Fiona, Slater, Rebeccah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087440/
https://www.ncbi.nlm.nih.gov/pubmed/33847561
http://dx.doi.org/10.7554/eLife.65266