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Quantifying noxious-evoked baseline sensitivity in neonates to optimise analgesic trials
Despite the high burden of pain experienced by hospitalised neonates, there are few analgesics with proven efficacy. Testing analgesics in neonates is experimentally and ethically challenging and minimising the number of neonates required to demonstrate efficacy is essential. EEG (electroencephalogr...
Autores principales: | Cobo, Maria M, Hartley, Caroline, Gursul, Deniz, Andritsou, Foteini, van der Vaart, Marianne, Schmidt Mellado, Gabriela, Baxter, Luke, Duff, Eugene P, Buckle, Miranda, Evans Fry, Ria, Green, Gabrielle, Hoskin, Amy, Rogers, Richard, Adams, Eleri, Moultrie, Fiona, Slater, Rebeccah |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087440/ https://www.ncbi.nlm.nih.gov/pubmed/33847561 http://dx.doi.org/10.7554/eLife.65266 |
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