MicroRNA-34a Promotes EMT and Liver Fibrosis in Primary Biliary Cholangitis by Regulating TGF-β1/smad Pathway

BACKGROUND AND AIMS: Primary biliary cholangitis (PBC) is an autoimmune cholestatic liver disease. We found microRNA-34a (miR-34a), as the downstream gene of p53, was overexpressed in some of fibrogenic diseases. In this study, we sought to explore whether miR-34a plays a role in the fibrosis of PBC...

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Detalles Bibliográficos
Autores principales: Pan, Ying, Wang, Jing, He, Lan, Zhang, Fengchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087466/
https://www.ncbi.nlm.nih.gov/pubmed/33977112
http://dx.doi.org/10.1155/2021/6890423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087466/
https://www.ncbi.nlm.nih.gov/pubmed/33977112
http://dx.doi.org/10.1155/2021/6890423

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