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CB(1) antagonism increases excitatory synaptogenesis in a cortical spheroid model of fetal brain development

The endocannabinoid system (ECS) plays a complex role in the development of neural circuitry during fetal brain development. The cannabinoid receptor type 1 (CB(1)) controls synaptic strength at both excitatory and inhibitory synapses and thus contributes to the balance of excitatory and inhibitory...

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Detalles Bibliográficos
Autores principales: Papariello, Alexis, Taylor, David, Soderstrom, Ken, Litwa, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087674/
https://www.ncbi.nlm.nih.gov/pubmed/33931678
http://dx.doi.org/10.1038/s41598-021-88750-2