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CB(1) antagonism increases excitatory synaptogenesis in a cortical spheroid model of fetal brain development
The endocannabinoid system (ECS) plays a complex role in the development of neural circuitry during fetal brain development. The cannabinoid receptor type 1 (CB(1)) controls synaptic strength at both excitatory and inhibitory synapses and thus contributes to the balance of excitatory and inhibitory...
Autores principales: | Papariello, Alexis, Taylor, David, Soderstrom, Ken, Litwa, Karen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087674/ https://www.ncbi.nlm.nih.gov/pubmed/33931678 http://dx.doi.org/10.1038/s41598-021-88750-2 |
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