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DNMT3A-mediated silence in ADAMTS9 expression is restored by RNF180 to inhibit viability and motility in gastric cancer cells

ADAMTS9 belongs to the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family, and its expression is frequently silenced due to promoter hypermethylation in various human cancers. However, the underlying mechanisms remain largely unknown. In this study, we investigate...

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Detalles Bibliográficos
Autores principales: Sun, Weilin, Ma, Gang, Zhang, Li, Wang, Pengliang, Zhang, Nannan, Wu, Zizhen, Dong, Yinping, Cai, Fenglin, Chen, Liqiao, Liu, Huifang, liang, Han, Deng, Jingyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087691/
https://www.ncbi.nlm.nih.gov/pubmed/33931579
http://dx.doi.org/10.1038/s41419-021-03628-5