Permissive effect of GSK3β on profibrogenic plasticity of renal tubular cells in progressive chronic kidney disease

Renal tubular epithelial cells (TECs) play a key role in renal fibrogenesis. After persistent injuries that are beyond self-healing capacity, TECs will dedifferentiate, undergo growth arrest, convert to profibrogenic phenotypes, and resort to maladaptive plasticity that ultimately results in renal f...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Bohan, Wang, Pei, Liang, Xianhui, Jiang, Chunming, Ge, Yan, Dworkin, Lance D., Gong, Rujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087712/
https://www.ncbi.nlm.nih.gov/pubmed/33931588
http://dx.doi.org/10.1038/s41419-021-03709-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087712/
https://www.ncbi.nlm.nih.gov/pubmed/33931588
http://dx.doi.org/10.1038/s41419-021-03709-5

Ejemplares similares