Cut-like homeobox 1 (CUX1) tumor suppressor gene haploinsufficiency induces apoptosis evasion to sustain myeloid leukemia

While oncogenes promote tumorigenesis, they also induce deleterious cellular stresses, such as apoptosis, that cancer cells must combat by coopting adaptive responses. Whether tumor suppressor gene haploinsufficiency leads to such phenomena and their mechanistic basis is unclear. Here, we demonstrat...

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Detalles Bibliográficos
Autores principales: Supper, Emmanuelle, Rudat, Saskia, Iyer, Vivek, Droop, Alastair, Wong, Kim, Spinella, Jean-François, Thomas, Patrick, Sauvageau, Guy, Adams, David J., Wong, Chi C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087769/
https://www.ncbi.nlm.nih.gov/pubmed/33931647
http://dx.doi.org/10.1038/s41467-021-22750-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087769/
https://www.ncbi.nlm.nih.gov/pubmed/33931647
http://dx.doi.org/10.1038/s41467-021-22750-8

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