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Bruton’s tyrosine kinase regulates gut immune homeostasis through attenuating Th1 response

Inflammatory bowel disease (IBD) is driven by multiple genetic and environmental risk factors. Patients with mutations in Bruton’s tyrosine kinase (BTK) is known to manifest high prevalence of intestinal disorders including IBD. Although BTK mediates the signaling of various immune receptors, little...

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Detalles Bibliográficos
Autores principales: Guan, Di, Wang, Zixi, Huo, Jianxin, Xu, Shengli, Lam, Kong-Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087775/
https://www.ncbi.nlm.nih.gov/pubmed/33931590
http://dx.doi.org/10.1038/s41419-021-03702-y