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Bruton’s tyrosine kinase regulates gut immune homeostasis through attenuating Th1 response
Inflammatory bowel disease (IBD) is driven by multiple genetic and environmental risk factors. Patients with mutations in Bruton’s tyrosine kinase (BTK) is known to manifest high prevalence of intestinal disorders including IBD. Although BTK mediates the signaling of various immune receptors, little...
Autores principales: | Guan, Di, Wang, Zixi, Huo, Jianxin, Xu, Shengli, Lam, Kong-Peng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087775/ https://www.ncbi.nlm.nih.gov/pubmed/33931590 http://dx.doi.org/10.1038/s41419-021-03702-y |
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