Designing and generating a single-chain fragment variable (scFv) antibody against IL2Rα (CD25): An in silico and in vitro study

OBJECTIVE(S): IL-2Rα plays a critical role in maintaining immune function. However, expression and secretion of CD25 in various malignant disorders and autoimmune diseases are now well established. Thus, CD25 is considered an important target candidate for antibody-based therapy. This study aimed to...

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Detalles Bibliográficos
Autores principales: Navabi, Parnian, Ganjalikhany, Mohamad Reza, Jafari, Sepideh, Dehbashi, Moein, Ganjalikhani-Hakemi, Mazdak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087844/
https://www.ncbi.nlm.nih.gov/pubmed/33995947
http://dx.doi.org/10.22038/ijbms.2021.51709.11728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087844/
https://www.ncbi.nlm.nih.gov/pubmed/33995947
http://dx.doi.org/10.22038/ijbms.2021.51709.11728

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