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Thiamine reduced metabolic syndrome symptoms in rats via down-regulation of hepatic nuclear factor-kβ and induction activity of glyoxalase-I

OBJECTIVE(S): Metabolic syndrome (MS) is a cause of death worldwide. The hepatic nuclear factor- NF-kβ (NF-kβ) is the cardinal player of hepatic homeostasis, insulin sensitivity, and lipid metabolism. Thus, we investigated the effect of thiamine on hepatic gene expression of NF-kβ and its levels of...

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Detalles Bibliográficos
Autores principales: Mahdavifard, Sina, Dehghani, Razieh, Jeddi, Farhad, Najafzadeh, Nowruz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087849/
https://www.ncbi.nlm.nih.gov/pubmed/33995940
http://dx.doi.org/10.22038/ijbms.2021.53707.12086