4‐phenylbutyric acid promotes hepatocellular carcinoma via initiating cancer stem cells through activation of PPAR‐α

BACKGROUND AND AIMS: 4‐phenylbutyric acid (4‐PBA) is a low molecular weight fatty acid that is used in clinical practice to treat inherited urea cycle disorders. In previous reports, it acted as a chemical chaperone inhibiting endoplasmic reticulum (ER) stress and unfolded protein response signaling...

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Detalles Bibliográficos
Autores principales: Chen, Shu‐Zhen, Ling, Yan, Yu, Le‐Xing, Song, Yu‐Ting, Chen, Xiao‐Fei, Cao, Qi‐Qi, Yu, Han, Chen, Can, Tang, Jiao‐Jiao, Fan, Zhe‐Cai, Miao, Yu‐Shan, Dong, Ya‐Ping, Tao, Jun‐Yan, Monga, Satdarshan P.S., Wen, Wen, Wang, Hong‐Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087947/
https://www.ncbi.nlm.nih.gov/pubmed/33931972
http://dx.doi.org/10.1002/ctm2.379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087947/
https://www.ncbi.nlm.nih.gov/pubmed/33931972
http://dx.doi.org/10.1002/ctm2.379

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