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CSF metabolites associate with CSF tau and improve prediction of Alzheimer's disease status

INTRODUCTION: Cerebrospinal fluid (CSF) total tau (t‐tau) and phosphorylated tau (p‐tau) are biomarkers of Alzheimer's disease (AD), yet much is unknown about AD‐associated changes in tau metabolism and tau tangle etiology. METHODS: We assessed the variation of t‐tau and p‐tau explained by 38 p...

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Detalles Bibliográficos
Autores principales: Dong, Ruocheng, Darst, Burcu F., Deming, Yuetiva, Ma, Yue, Lu, Qiongshi, Zetterberg, Henrik, Blennow, Kaj, Carlsson, Cynthia M., Johnson, Sterling C., Asthana, Sanjay, Engelman, Corinne D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087982/
https://www.ncbi.nlm.nih.gov/pubmed/33969169
http://dx.doi.org/10.1002/dad2.12167