The extracellular HDAC6 ZnF UBP domain modulates the actin network and post-translational modifications of Tau

BACKGROUND: Microtubule-associated protein Tau undergoes aggregation in Alzheimer`s disease (AD) and a group of other related diseases collectively known as Tauopathies. In AD, Tau forms aggregates, which are deposited intracellularly as neurofibrillary tangles. Histone deacetylase-6 (HDAC6) plays a...

Descripción completa

Detalles Bibliográficos
Autores principales: Balmik, Abhishek Ankur, Sonawane, Shweta Kishor, Chinnathambi, Subashchandrabose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8088071/
https://www.ncbi.nlm.nih.gov/pubmed/33933071
http://dx.doi.org/10.1186/s12964-021-00736-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8088071/
https://www.ncbi.nlm.nih.gov/pubmed/33933071
http://dx.doi.org/10.1186/s12964-021-00736-9

Ejemplares similares