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The extracellular HDAC6 ZnF UBP domain modulates the actin network and post-translational modifications of Tau

BACKGROUND: Microtubule-associated protein Tau undergoes aggregation in Alzheimer`s disease (AD) and a group of other related diseases collectively known as Tauopathies. In AD, Tau forms aggregates, which are deposited intracellularly as neurofibrillary tangles. Histone deacetylase-6 (HDAC6) plays a...

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Detalles Bibliográficos
Autores principales:	Balmik, Abhishek Ankur, Sonawane, Shweta Kishor, Chinnathambi, Subashchandrabose
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8088071/ https://www.ncbi.nlm.nih.gov/pubmed/33933071 http://dx.doi.org/10.1186/s12964-021-00736-9

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