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CoLiDe: Combinatorial Library Design tool for probing protein sequence space

MOTIVATION: Current techniques of protein engineering focus mostly on re-designing small targeted regions or defined structural scaffolds rather than constructing combinatorial libraries of versatile compositions and lengths. This is a missed opportunity because combinatorial libraries are emerging...

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Detalles Bibliográficos
Autores principales: Tretyachenko, Vyacheslav, Voráček, Václav, Souček, Radko, Fujishima, Kosuke, Hlouchová, Klára
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8088326/
https://www.ncbi.nlm.nih.gov/pubmed/32956450
http://dx.doi.org/10.1093/bioinformatics/btaa804