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MR-Clust: clustering of genetic variants in Mendelian randomization with similar causal estimates
MOTIVATION: Mendelian randomization is an epidemiological technique that uses genetic variants as instrumental variables to estimate the causal effect of a risk factor on an outcome. We consider a scenario in which causal estimates based on each variant in turn differ more strongly than expected by...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8088327/ https://www.ncbi.nlm.nih.gov/pubmed/32915962 http://dx.doi.org/10.1093/bioinformatics/btaa778 |