HIF1α-dependent induction of the mitochondrial chaperone TRAP1 regulates bioenergetic adaptations to hypoxia

The mitochondrial paralog of the Hsp90 chaperone family TRAP1 is often induced in tumors, but the mechanisms controlling its expression, as well as its physiological functions remain poorly understood. Here, we find that TRAP1 is highly expressed in the early stages of Zebrafish development, and its...

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Detalles Bibliográficos
Autores principales: Laquatra, Claudio, Sanchez-Martin, Carlos, Dinarello, Alberto, Cannino, Giuseppe, Minervini, Giovanni, Moroni, Elisabetta, Schiavone, Marco, Tosatto, Silvio, Argenton, Francesco, Colombo, Giorgio, Bernardi, Paolo, Masgras, Ionica, Rasola, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8088431/
https://www.ncbi.nlm.nih.gov/pubmed/33934112
http://dx.doi.org/10.1038/s41419-021-03716-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8088431/
https://www.ncbi.nlm.nih.gov/pubmed/33934112
http://dx.doi.org/10.1038/s41419-021-03716-6

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